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KMID : 0939920150470040897
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대한암학회지
2015 Volume.47 No. 4 p.897 ~ p.903
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Long-term Outcome of Chondrosarcoma: A Single Institutional Experience
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Srimanth Bindiganavile
Han Il-Kyu
Yun Ji-Yeon
Kim Han-Soo
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Abstract
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Purpose: The prognostic factors of chondrosarcoma remain uncertain as only a few large studies with long-term follow-up have been reported. The aim of this study was to analyze oncological outcomes and prognostic factors.
Materials and Methods: A retrospective review of oncological outcomes and prognostic factors was performed on 125 consecutive chondrosarcoma patients who underwent surgery at our institution.
Results: Overall survival was 91.6%±2.5%, 84.1%±3.8%, and 84.1%±3.8% at 5, 10, and 15 years respectively. Among the histological types, dedifferentiated type showed the worst survival (p < 0.001). As for conventional type chondrosarcoma, histologic grade and anatomical location predicted outcome, with high-grade with axial location having the worst outcome (p < 0.001). In contrast, low-grade chondrosarcoma of appendicular skeleton could be treated safely by intralesional curettage.
Conclusion: Histological type was significantly associated with the outcome of chondrosarcoma. For the conventional type, histologic grade and anatomical location predicted outcome, with high-grade with axial location having the worst outcome.
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KEYWORD
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Chondrosarcoma, Prognosis, Recurrence, Pelvis, Histology
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